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Cinchocaine/Hydrocortisone/Framycetin/Aesculin ointment (Proctosedyl® ointment)

Proctosedyl®ointment is used to relieve symptoms from piles. Learn how to use the medication, its common side effects, special precautions to watch out for, and more.
  • Article last reviewed 21 July 2026
  • 7 mins read

What is this medication for?

Proctosedyl® contains four medications: cinchocaine, hydrocortisone, framycetin and aseculin.

The ingredients composition in Proctosedyl® ointment may varies by product source. Please consult a pharmacist if you have any allergy concerns. 

Cinchocaine temporarily numbs the area where it is applied. This reduces pain and muscle spasms of the rectum. Cinchocaine is also known as dibucaine in some preparations.

Hydrocortisone is a steroid that works by reducing the production of substances that cause inflammation. This helps to reduce swelling, itching and discharge.

Framycetin is an antibiotic that helps fight infections. Framycetin is also known as Neomycin B in some preparations. 

Aseculin protects and strengthens blood vessels to reduce swelling. Aseculin is also known as esculin or esculoside in some preparations. 

Proctosedyl® ointment is used for short-term relief of pain, irritation, discharge and itching caused by enlarged or swollen blood vessels around or inside your rectum (piles).

How should I take or use this medication?

  • This medication may be taken when needed to relieve the symptoms from piles. It is not always necessary to use it regularly. Please check with your healthcare professional if you are unsure.
  • Do not use longer than the duration recommended by your healthcare professional.
  • Only apply to your rectum and surrounding areas.


Technique of using Proctosedyl® ointment:

  • Apply as instructed by your doctor.
  • Wash your hands before and after applying.

For external use around the rectum:

  • Squeeze a small amount onto your fingertip.
  • Gently rub a thin layer over the sore, painful or itchy area.

For internal use deeper into the rectum:

  • Screw the plastic nozzle onto the tube.
  • Insert the nozzle into the rectum.
  • Squeeze the tube gently as you slowly pull it out.
  • Stay still for 1 to 2 minutes.
  • Wash your hands and the nozzle.

What should I do if I forget to take or use this medication?

This medication may be used when needed to relieve the symptoms from piles, it is not always necessary to use it regularly. Please check with your healthcare professional if you are unsure.

What precautions should I take when taking or using this medication?

Inform your healthcare professional if:

  • You are allergic to this medication or any of the other ingredients of this medication.

This medicine contains wool fat (lanolin) which may cause local skin reactions such as contact dermatitis. Signs of contact dermatitis includes redness, itching or irritation of the skin.

If you have any question about this medication, please discuss with your healthcare professional.

What are some common side effects of this medication? ​

  • Skin rash

  • Itching or burning sensation around the rectum

  • Skin changes with long-term use such as thinning, small blood vessels showing through, and bruising more easily

Speak with your healthcare professionals if any of these side effects continues, worsens, or affects your daily life.

What are some rare but serious side-effects that I need to seek medical advice immediately? 

The symptoms of a drug allergy include one or more of the following:

  • Swollen face/eyes/lips/tongue

  • Difficulty in breathing

  • Itchy skin rashes over your whole body

You can also find out about drug allergies by watching these videos:

For videos in 中文, Melayu and தமிழ், click here
 

If you have used this medication for a long time, these side effects may occur:

  • The adrenal glands (glands on top of your kidneys) may stop producing enough hormone on their own. Signs include lack of appetite, stomach pain, weight loss, feeling sick or vomiting, lack of concentration, feeling hungry, nervousness.

  • Visual disturbanes such as blurred vision.

Signs of a skin infection around the rectum area such as increased redness, swelling, warmth, pain or discharge.

If you experience any of these symptoms, you should stop your medication and see your healthcare professional immediately.

What food or medication should I avoid when I take or use this medication?

There are no known significant food or drug interactions with this medication.

How should I store this medication?

Store below 25°C, away from direct sunlight. Keep this medication away from children.

How do I throw away this medication safely? ​

Pack this medication into a black trash bag and seal it tightly before throwing into the rubbish chute or bin.

Disclaimer

Please take note that the above is not a complete list of all possible side-effects. If you have any concerns about your medication or if you have other side-effects that you think are caused by this medication, please consult your doctor or pharmacist. If you take more than the recommended dose, please seek medical advice immediately. The information provided on this page does not replace information from your healthcare professional. Please consult your healthcare professional for more information. 

This article is jointly developed by members of the National Medication Information workgroup. The workgroup consists of cluster partners (NHG Health, National University Health System and SingHealth), community pharmacies (Guardian, Unity and Watsons) and Pharmaceutical Society of Singapore. The content does not reflect drug availability and supply information in pharmacies and healthcare institutions. You are advised to check with the respective institutions for such information.