Text Size :
Medications Banner.png

Clarithromycin

Clarithromycin is an antibiotic used to treat infections. Learn how to use the medication, its common side effects, special precautions to watch out for, and more.
  • Article last reviewed 09 October 2026
  • 6 mins read

What is this medication for?

Clarithromycin belongs to a class of antibiotics known as macrolides. It is used to treat bacterial infections, such as in the respiratory tract and Helicobacter pylori infection.

This medication may also be used for other conditions as determined by your doctor.

 

You can also find out about this medication by watching these videos:

For videos in 中文, Melayu and தமிழ், click here.

How should I take or use this medication?

  • Clarithromycin comes in tablet and suspension form. It can be taken with or without food.
  • For suspension, shake the bottle well before each use.
  • You should complete each course of antibiotics as prescribed by your doctor even if you feel better. Incomplete treatment might cause the infection to return or lead to antibiotic resistance. When antibiotic resistance happens, the antibiotic will not be effective anymore.

What should I do if I forget to take or use this medication?

If you forget to take a dose, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and take the next dose at the usual scheduled time. Do not take two doses to make up for the missed dose.

What precautions should I take when taking or using this medication?

Inform your healthcare professional if:

  • You are allergic to this medication or any of the other ingredients of this medication
  • You have myasthenia gravis (a disease that causes muscle weakness)
  • You ever had heart issues e.g. abnormal heartbeats or prolonged QT interval on ECG
  • You are taking medications to treat irregular heartbeats
  • You are pregnant, planning to become pregnant, or breastfeeding
  • You are taking any other medications, including supplements, traditional medications and herbal remedies

What are some common side effects of this medication? ​

  • Nausea/vomiting, stomach discomfort, diarrhoea
    • Take the medication with or after food.
    • If diarrhoea occurs, drink plenty of water to prevent dehydration.
    • If you experience persistent diarrhoea or stomach pain, do seek medical advice immediately.

What are some rare but serious side-effects that I need to seek medical advice immediately? 

The symptoms of a drug allergy include one or more of the following:

  • Swollen face/eyes/lips/tongue
  • Difficulty in breathing
  • Itchy skin rashes over your whole body

 

You can also find out about drug allergies by watching these videos:

 

For videos in 中文, Melayu and தமிழ், click here.

 

Other rare side effects include:

  • Liver damage
    • Yellowing of your skin and whites of the eyes
    • Dark coloured urine or light-coloured stools
    • Nausea and vomiting that does not go away
    • Loss of appetite
    • Stomach pain
  • Irregular or fast heartbeats
    • Symptoms include light headedness, dizziness or heart palpitations.

 

If you experience any of these symptoms, you should stop your medication and see your healthcare professional immediately.

What food or medication should I avoid when I take or use this medication?

Clarithromycin may affect the levels of other medications in your body. Inform your healthcare providers if you are on long term medications for additional advice, especially if you are on medications to manage your cholesterol (eg simvastatin, lovastatin).

How should I store this medication?

Store in a cool and dry place, away from direct sunlight. Keep this medication away from children.

Clarithromycin Suspension: Follow the storage and expiry date as stated on the bottle or as advised by your healthcare professionals.

How do I throw away this medication safely? ​

Pack the medication into a bag and bring it back to the pharmacy where you received the medication from.

Disclaimer

Please take note that the above is not a complete list of all possible side-effects. If you have any concerns about your medication or if you have other side-effects that you think are caused by this medication, please consult your doctor or pharmacist. If you take more than the recommended dose, please seek medical advice immediately. The information provided on this page does not replace information from your healthcare professional. Please consult your healthcare professional for more information. 

This article is jointly developed by members of the National Medication Information workgroup. The workgroup consists of cluster partners (NHG Health, National University Health System and SingHealth), community pharmacies (Guardian, Unity and Watsons) and Pharmaceutical Society of Singapore. The content does not reflect drug availability and supply information in pharmacies and healthcare institutions. You are advised to check with the respective institutions for such information.