Text Size :
Medications Banner.png

Brinzolamide Eye Drop

Brinzolamide is used to reduce eye pressure and treat glaucoma. Learn how to use the medication, its common side effects, special precautions to watch out for, and more.
  • Article last reviewed 06 April 2026
  • 7 mins read

What is this medication for?

Brinzolamide belongs to a class of medications called carbonic anhydrase inhibitors, which is used to treat glaucoma. Glaucoma is a condition where the nerve in the eye is damaged, and is usually associated with increased eye pressure. Untreated glaucoma can affect your eyesight and cause blindness. Brinzolamide helps to lower the pressure in your eye by reducing production of fluid in the eye.

Brinzolamide may also be used for other indications as prescribed by your doctor.

How should I take or use this medication?

  • Proper use of eye drop
    • Wash your hands with soap and water, and read the instructions on the label.
    • While seated, tilt your head backwards and look up. You may also lie down. 
    • Using your index finger, gently pull down the lower eyelid to form a pocket and instil one drop into the eye. Make sure the tip does not touch the eye or any other surface to prevent it from getting dirty.
    • Close your eyes gently and wipe off any excess eye drops around your eyes with a clean tissue.
    • Keep your eyes closed and press down gently on the inner corner of your eye for 1 to 2 minutes to allow the medication to be absorbed.
    • If you need to use more than 1 drop of medication, or if you are using another type of eye drop, wait at least 5 to 10 minutes before applying the next eye drop. 
  • For more details on how to apply eye drops, click on this link for a step-by-step guide: https://www.healthhub.sg/medication-devices-and-treatment/medications/a-step-by-step-guide-on-how-to-instil-eye-drops
  • Do not stop using your medication without checking with your healthcare professional.

What should I do if I forget to take or use this medication?

If you forget to use a dose, use it as soon as you remember if it is not close to the next dose. Otherwise, you should skip the dose and use the next dose at the usual time. Do not use two doses together to make up for the missed dose.   

What precautions should I take when taking or using this medication?

Inform your healthcare professional if: 

  • You are allergic to this medication or any of the other ingredients of this medication, or if you have a sulfa (sulfonamide) allergy .
  • You are pregnant, planning to become pregnant, or breastfeeding .
  • You are taking any other medications, including supplements, traditional medications and herbal remedies. 

What are some common side effects of this medication? ​

  • Stinging or burning sensation in the eye
  • Eye redness
  • Eye itch
  • Eye irritation
  • Blurred vision
    • If you experience blurred vision, do not drive or operate any machinery until your vision is clear.
  • Taste disturbance (bitter or unusual taste in the mouth)
    • After instilling the eye drop, close your eyes and press down gently on the inner corner of the eye for 1 to 2 minutes. It may help to reduce this side effect.
  • Headache

If these side effects happen and do not go away, check with your healthcare professional as soon as possible.

What are some rare but serious side-effects that I need to seek medical advice immediately? 

The symptoms of a drug allergy include one or more of the following:

  • Swollen face/eyes/lips/tongue
  • Difficulty in breathing
  • Itchy skin rashes around your eyes or over your whole body

If you experience any of these symptoms, you should stop your medication and see your healthcare professional immediately.

How should I store this medication?

Store in a cool and dry place, away from direct sunlight. Keep this medication away from children. 

Record the date opened on the eye drop bottle. Discard this medication one month after opening. 

How do I throw away this medication safely? ​

Pack this medication into a black trash bag and seal it tightly before throwing into the rubbish chute or bin.

Disclaimer

Please take note that the above is not a complete list of all possible side-effects. If you have any concerns about your medication or if you have other side-effects that you think are caused by this medication, please consult your doctor or pharmacist. If you take more than the recommended dose, please seek medical advice immediately. The information provided on this page does not replace information from your healthcare professional. Please consult your healthcare professional for more information.

This article is jointly developed by members of the National Medication Information workgroup. The workgroup consists of cluster partners (NHG Health, National University Health System and SingHealth), community pharmacies (Guardian, Unity and Watsons) and Pharmaceutical Society of Singapore. The content does not reflect drug availability and supply information in pharmacies and healthcare institutions. You are advised to check with the respective institutions for such information.