Sodium Valproate

Sodium valproate is used to control some types of seizures, (commonly known as fits). It can also be used as a mood stabilizer. Patients who have bipolar disease have serious mood swings and sodium valproate helps to reduce the seriousness of these mood swings.

What is this medication used for

Sodium valproate is used to control some types of seizures, (commonly known as fits). It can also be used as a mood stabilizer. Patients who have bipolar disease have serious mood swings and sodium valproate helps to reduce the seriousness of these mood swings.

This medicine can also be used in other medical conditions such as prevention of migraine headaches.

Dosage and How to Use

  • Do not stop taking your medicines without checking with your doctors.

  • If you miss a dose, take the missed dose as soon as you remember. If it is almost time for your next dose, take only the usual dose. Do not double your dose or use extra medicine to make up for the missed dose.

  • Follow the dose given on your medicine label. Do not take more or less of it or take it more often than that instructed by your doctor.

  • You should continue to take your medicines regularly as instructed by your doctor even if you feel well. Stopping your medicines without informing your doctor may cause your condition to become worse quickly.

  • Some sodium valproate tablets are made into enteric coated or controlled release forms. Extended-release forms of sodium valproate provide a slow and continuous supply of medicine into your body. Enteric coated forms of sodium valproate reduce stomach upset caused by the medicine. If you are taking enteric coated or controlled release forms of sodium valproate, you should swallow the tablet whole. Do not crush or chew these forms of sodium valproate.

  • If you are taking the syrup form of sodium valproate, you should not mix the medicine with any carbonated drink.

  • You can take this medicine with or after food.

Side Effects, Precautions, Contraindication

What are the possible side effects of the medicine?

The common side effects of sodium valproate include:

  • Dizziness or feeling light-headed

  • Drowsiness

  • Nausea, vomiting, stomach upset or stomach cramp

  • Slight temporary hair loss at the beginning when you start to use the medicine

  • Increase in appetite, weight gain

  • Trembling of hands and arms

These symptoms may happen but should get better over time. Check with your doctor if any of these symptoms are serious or do not go away.

If the following serious side effects happen, you should check with your doctor immediately:

  • Unusual bleeding or bruising

  • Yellowing of eyes or skin (Jaundice)

  • Losing appetite a lot, stomach pain or vomiting that does not go away

  • Feeling very weak or dizzy

  • Blurred vision or double vision

  • Feelings of confusion or thoughts about harming or killing yourself

How do I know if I am allergic to this medicine?

The symptoms of a drug allergy include one or more of the following:

  • Swollen face/eyes/lips

  • Difficulty in breathing

  • Itchy skin rashes over your whole body

If you experience any of these symptoms, you should stop your medicine immediately and see your doctor.

What precaution s should I follow when taking the medicine?

  • You should inform your doctor if you have the following medical conditions before starting on sodium valproate:

    • Liver or kidney problems

    • Pancreas problems

    • Blood-related diseases

    • Urea cycle disorder

  • If you are pregnant or planning to get pregnant or are breastfeeding, you should inform your doctor.

  • Be careful when driving or operating machinery as this medicine may cause drowsiness or blurred vision. Do not take alcohol and other medicines that make you less alert.

  • If you are taking other medicines, sodium valproate may affect how they work. Please see your doctor or pharmacist before using any other medicines, including over-the-counter medicines, vitamins and herbal products. Please make sure that the doctor who treats you knows that you are on sodium valproate.

  • See your doctor immediately if your seizures get worse or become different after you start using this medicine.

Handling and Storage

  • Keep your medicines in the original container or packaging, tightly closed or sealed in a cool and dry place, away from direct sunlight.

  • Keep the medicine out of reach of children.

  • Throw away all expired medicines.


​​This medicine has been proven to be safe and effective, but it can cause serious injury if a mistake happens while taking it. This means that it is very important for you to know about this medicine and take it exactly as directed.

This article answers some common questions about this medicine. It does not contain all the available information. It also does not take the place of talking to your doctor or pharmacist.

PH004-011-E-0117-V2

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Sodium Valproate

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