Rituximab

What is this medication for?

• This medication is used to treat rheumatoid arthritis, some types of cancer, and skin conditions.
• It is usually used when other common medications cannot be used or did not work well enough.
• For the treatment of skin conditions, you may start to see an improvement in your condition 2-16 weeks after treatment and the effects of this medication generally last up to 6-9 months.
• For the treatment of rheumatoid arthritis, you may start to see an improvement in your condition 6 weeks after treatment, the effects of this medication generally last up to 9 months.

How should I take or use this medication?

• This medication is given through a drip into a vein using needle as an infusion, in a healthcare facility. Each infusion usually takes several hours.
• For some types of cancer, rituximab may be given as a injection into the fat layer under the skin.
• Your doctor will decide the dose of medication for you and how often you should receive it.

What precautions should I take when taking or using this medication?

• Avoid going to crowded places with many people as this medication may reduce your body’s ability to fight against infection.
• Inform your healthcare professional if:
  • You are allergic to this medication or any of the ingredients of this medication.
  • You are pregnant, planning to become pregnant, or breastfeeding.
    • Effective birth control should be used during and for at least 12 months after treatment.
    • Breastfeeding should be avoided during and for at least 6 months after treatment.
  • You have a condition or are receiving treatment that affects your immune system including: cancer, human immunodeficiency virus (HIV) infection, acquired immunodeficiency syndrome (AIDS).
  • You have any active infections, especially tuberculosis (TB) or hepatitis, or have recently been near anyone who might have TB.
  • You have other conditions such as heart failure or nervous system disorders.
  • You are going for a vaccination or a surgery, including dental surgery.
  • You are taking or intend to take any other medications, supplements, traditional medications, or herbal remedies, including those that are over-the-counter.

What are some common side effects of this medication? ​

• During the vein infusion, you may experience infusion reactions (fever with chills, drop in blood pressure, skin itch, mild throat tightening, skin rash).
  • You may be given medications such as paracetamol, antihistamines and/or steroids before the infusion to prevent or reduce these side effects.
  • Inform the nurse immediately if you experience any of these symptoms.
  • Your infusion may be slowed down or stopped if the side effects are severe.
• Other common side effects include nausea, tiredness, body aches.

What are some rare but serious side-effects that I need to seek medical advice immediately? 

Consult your doctor if you notice any of the following side effect(s) during or after the infusion:

What food or medication should I avoid when I take or use this medication?

• Avoid eating raw or undercooked food e.g., soft cheeses, soft-boiled eggs as this medication may reduce your body’s ability to fight against infection.
• Inform your healthcare professional if you are taking or intend to take any other medications, supplements, traditional medications, or herbal remedies, including those that are over-the-counter.