Nausea and Vomiting Medications in Pregnancy
- Article last reviewed 12 June 2025
- 9 mins read
What is nausea and vomiting in pregnancy?
Nausea and vomiting in pregnancy (NVP) is a common part of pregnancy for many women. It is commonly known as “morning sickness” but the symptoms can occur at any time of the day. These symptoms can be unpleasant and affect your daily activities. It usually occurs within the first 12 weeks of pregnancy (first trimester). However, for some women, it may last longer or even throughout pregnancy.
What medications can help nausea and vomiting?
In most cases, NVP does not need treatment with medication. See a doctor if your symptoms are severe or affecting your daily life.
There are many medications that have shown to be safe to use during pregnancy to treat NVP. The table below lists some of the common medications that may be used. You should take your medications as instructed by your doctor or pharmacist.
| Medication | How should I take/use this medication? | What are some possible side-effects, and how to manage? |
| Pyridoxine (Vitamin B6) |
|
|
Bonjesta® (Contains doxylamine and pyridoxine) |
|
|
| Promethazine Teoclate |
|
|
| Metoclopramide |
|
|
| Ondansetron |
|
|

What should I do if I forget to take/use this medication?
Medications for nausea and vomiting are to be taken only when necessary. If you have no symptoms, you do not need to take the medication.
What else can I do?
Do’s
| Don’ts
|
What precautions should I take?
Inform your healthcare professional if:
- You are allergic to the medications prescribed or any of the other ingredients of the medication
- You are taking any other medications, including supplements, traditional medications and herbal remedies.
- Nausea and vomiting becomes severe and you experience signs of dehydration or weight loss. Signs of dehydration include feeling ‘dry’ or very thirsty, becoming drowsy or unwell, or your urine changing from light yellow to dark yellow or brown colour.
What are some rare but serious side-effects that I need to seek medical advice immediately?
The symptoms of a drug allergy include one or more of the following:
- Swollen face/eyes/lips/tongue
- Difficulty in breathing
- Itchy skin rashes over your whole body
If you experience any of these symptoms, you should stop your medication and see your healthcare professional immediately.
How should I store these medications?
Store in a cool and dry place, away from direct sunlight. Keep this medication away from children.
How should I throw away these medications safely?
Pack the medication into a black trash bag and seal it tightly before throwing it into the rubbish chute or bin.
Disclaimer
The content of this article does not replace the information from your healthcare professional. Please consult your healthcare professional for more information.
This article is jointly developed by members of the National Medication Information workgroup. The workgroup consists of cluster partners (NHG Health, National University Health System and SingHealth), community pharmacies (Guardian, Unity and Watsons) and Pharmaceutical Society of Singapore (PSS).
The images and video in this article has been developed by the Singapore National Asthma Programme (SNAP) and have been reviewed by the PSS-National Medication Information workgroup.
Contributed By
- Pharmaceutical Society of Singapore