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Choline salicylate oral gel

Choline salicylate oral gel is used to treat teething pain, mouth ulcers, denture irritation and cold sores. Learn how to use the medication, its common side effects, special precautions to watch out for, and more.
  • Article last reviewed 12 June 2026
  • 6 mins read

What is this medication for?

Choline salicylate oral gel is used to treat teething pain, mouth ulcers, denture irritation, and cold sores. Choline salicylate is a non-steroidal anti-inflammatory drug (NSAID) which relieves pain and inflammation. Some products may also include an antiseptic ingredient such as Cetalkonium chloride or Cetylpyridinium chloride to prevent infection.

How should I take or use this medication?

  • Use this medication as recommended by your healthcare professional. Consult your healthcare professional if you are not sure how to use this medication correctly.
  • Apply the gel with a washed finger, rubbing into the affected area every 3 hours when needed.
  • When treating ulcers, the surface of the ulcer should be wiped free of mucus before applying the gel to allow the gel to stick more firmly.
  • For denture irritation, massage the gel onto the sore area and wait at least 30 minutes before reinserting the dentures. Do not apply the gel directly on the dentures.
  • Do not use in infants under 4 months old.

What should I do if I forget to take or use this medication?

Choline salicylate oral gel may be used when required for a short period of time. This means you no longer have to use it if you do not have any more symptoms. If you miss a dose, use it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue normally. Do not use two doses or extra medication to make up for the missed dose.

What precautions should I take when taking or using this medication?

Inform your healthcare professional if:

  • You are allergic to salicylates, NSAIDs (e.g. aspirin), this medication or any of the other ingredients of this medication.
  • You are taking any other medications, including supplements, traditional medications, and herbal remedies.

If you have any questions about this medication, please discuss with your healthcare professional.

What are some common side effects of this medication? ​

You may feel a temporary tingling sensation when you apply this medication.

This side effect is usually mild and goes away after some time. However, if the symptom is bothersome, does not go away or becomes worse, stop this medication and consult your healthcare professional.

What are some rare but serious side-effects that I need to seek medical advice immediately? 

The symptoms of a drug allergy include one or more of the following:

  • Swollen face/eyes/lips/tongue
  • Difficulty in breathing
  • Itchy skin rashes over your whole body

If you experience any of these symptoms, you should stop your medication and see your healthcare professional immediately.

You can also find out about drug allergies by watching these videos:

For videos in 中文, Melayu and தமிழ், click here

What food or medication should I avoid when I take or use this medication?

Inform your healthcare professional if you are taking, or planning to take any other herbal products, supplements or medications.

How should I store this medication?

Store in a cool and dry place, away from direct sunlight. Keep this medication away from children. 

How do I throw away this medication safely? ​

Pack this medication into a black trash bag and seal it tightly before throwing into the rubbish chute or bin.

Disclaimer

Please take note that the above is not a complete list of all possible side-effects. If you have any concerns about your medication or if you have other side-effects that you think are caused by this medication, please consult your doctor or pharmacist. If you take more than the recommended dose, please seek medical advice immediately. The information provided on this page does not replace information from your healthcare professional. Please consult your healthcare professional for more information. 

This article is jointly developed by members of the National Medication Information workgroup. The workgroup consists of cluster partners (NHG Health, National University Health System and SingHealth), community pharmacies (Guardian, Unity and Watsons) and Pharmaceutical Society of Singapore. The content does not reflect drug availability and supply information in pharmacies and healthcare institutions. You are advised to check with the respective institutions for such information.