Medication Information Leaflet
Spironolactone belongs to a class of medications called Mineralocorticoid Receptor Antagonist (MRA). It works on your kidneys to remove extra water and salts in your body. This will decrease the pressure on the blood vessels and allow the heart to work less hard. It is also used to reduce the amount of fluid present in the lungs as a result of heart failure.
Heart failure is a condition where the heart is weak and is unable to pump enough blood to the rest of the body. This medication is used in heart failure to improve the survival rate, reduce the symptoms of heart failure such as breathlessness or leg swelling and reduce the chance of being admitted to the hospital because of heart failure.
This medication may also be used to treat high blood pressure or high aldosterone (a type of hormone) levels.
If you miss a dose, take the missed dose as soon as you remember. If it is almost time for your next dose, take only the usual dose. Do not double your dose or use extra medication to make up for the missed dose.
Inform your healthcare professional if:
Some side effects may include:
Inform your healthcare professional if these side effects do not go away and become bothersome to you.
The symptoms of a drug allergy include one or more of the following:
If you experience any of these symptoms, you should stop your medication and see your healthcare professional immediately.
Store in a cool and dry place, away from direct sunlight. Keep this medication away from children. Throw away all expired medications.
Pack this medication into a black trash bag and seal it tightly before throwing into the rubbish chute or bin.
If you take more than the recommended dose, please seek medical advice immediately. The information provided on this page does not replace information from your healthcare professional. Please consult your healthcare professional for more information.
This article is jointly developed by members of the National Medication Information workgroup. The workgroup consists of cluster partners (National Healthcare Group, National University Health System and SingHealth), community pharmacies (Guardian, Unity and Watsons) and Pharmaceutical Society of Singapore. The content does not reflect drug availability and supply information in pharmacies and healthcare institutions. You are advised to check with the respective institutions for such information.
Last updated on July 2019
This article was last reviewed on Monday, September 13, 2021