Medication Information Leaflet
Lorlatinib is used to treat non-small cell lung cancer that has spread to other parts of the body. Your doctor will check for an alteration in your genes before starting you on this.
Take Lorlatinib once a day
You may take it with or without food
Do not break or crush the tablet. Swallow the tablet whole.
If you forget to take a dose, take it as soon as you remember if there is at least four hours before your next dose. If not, skip the missed dose and take your next dose at the usual time. Do not take two doses at the same time.
Inform your healthcare professional if:
You are allergic to this medication
You or your partner becomes pregnant or is planning for pregnancy. You should use effective birth control during and for at least:
Six months after stopping treatment (for women)
Three months after stopping treatment (for men)
You are breastfeeding
You have any other medical conditions such as high cholesterol or heart problems
You are taking or intend to take any other medication, supplements, traditional medications or herbal remedies
Increased cholesterol and lipid levels
Swelling of hands, feet or lower legs
Numbness and tingling feeling in the joints, arms or legs
Joint or muscle aches
Changes in mood and thinking
Feeling tired and lack of energy
Symptoms of a drug allergy including one or more of the following:
Difficulty in breathing
Itchy skin rashes over your whole body
Sudden onset of cough, chest pain, shortness of breath, with fever
Dark urine or light coloured stools, nausea, vomiting, loss of appetite, stomach pain, yellowing of your eyes or skin
Low mood feeling that does not go away
Unusual giddiness or light-headedness
Slow or abnormal heartbeat
If you experience any of these symptoms, you should stop your medication and see your healthcare professional immediately.
Avoid taking grapefruit or grapefruit juice when you are taking this medication as it may interact with your medication and increase the risk of side-effects.
Store in a cool and dry place, away from direct sunlight. Keep this medication away from children.
This article was last reviewed on
Wednesday, November 22, 2023
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