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When you have diabetes, you may need to learn how to inject yourself with insulin.
Time of Start of Action (hours after administration)
Time of Maximum Action (hours after administration)
How Long Action lasts (hours after administration)
Rapid-acting · Lispro
Short-acting · Humulin® R · Actrapid® HM
Half hour Half hour
2-4 hours 1-3 hours
6-8 hours 6-8 hours
Intermediate-acting · Humulin® N/NPH human insulin . Humulin® L/lente human insulin . Insulatard® HM . Monotard® HM
1-2 hours 1-3 hours 1.5 hours 2.5 hours
6-12 hours 6-12 hours 4-12 hours 7-15 hours
18-24 hours 18-24 hours 18-24 hours Up to 24 hours
Long-acting . Humulin® U
Up to 24 hours
** Low blood sugar (hypo) reaction is more likely to occur around the time of maximum action. High blood sugar (hyper) reaction is more likely to occur before the insulin starts acting, or when its action is ending.
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This article was last reviewed on
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