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Metronidazole Gel

Metronidazole gel is used to treat rosacea. Learn how to use the medication, its common side effects, special precautions to watch out for, and more.
  • Article last reviewed 20 January 2026
  • 5 mins read

What is this medication for?

Metronidazole gel is used on the skin to treat rosacea by reducing inflammation. You can read more about rosacea by clicking on this link: Rosacea: Symptoms and Treatment

How should I take or use this medication?

  • Use this medication as recommended by your healthcare professional. Consult your healthcare professional if you are not sure how to use this medication correctly.
  • Areas to be treated should be cleansed and dried before application of the gel.
  • Apply and rub in a thin film of gel to the affected areas, as specified by your healthcare professional.
  • Patients may use cosmetics after waiting for at least 5 minutes following application. to allow the medication to dry.
  • Avoid contact of the gel with eyes as it may cause eye irritation.

What should I do if I forget to take or use this medication?

If you forget to use the medication, apply the missed dose as soon as you remember. If it is almost time for your next application, only apply the usual amount. Do not double the amount of gel or apply extra medication to make up for the missed application.

What precautions should I take when taking or using this medication?

Inform your healthcare professional if: 

  • You are allergic to metronidazole or any of the other ingredients of this medication
  • You have any blood-related medical conditions
  • Local irritation occurs after using the gel

What are some common side effects of this medication? ​

  • Irritation, dryness or redness of the skin
  • Tearing or burning sensation of the eyes

You may be advised to use the medication less frequently, or discontinue use temporarily, or discontinue use until further instructions, if the side effects occur. Check with your healthcare professional on the advice for your situation.

What are some rare but serious side-effects that I need to seek medical advice immediately? 

The symptoms of a drug allergy include one or more of the following: 

  • Swollen face/eyes/lips/tongue
  • Difficulty in breathing
  • Itchy skin rashes over your whole body

If you experience any of these symptoms, you should stop your medication and see your healthcare professional immediately.

What food or medication should I avoid when I take or use this medication?

There are no specific foods or medications you need to avoid when using this medication.

How should I store this medication?

Store in a cool and dry place, away from direct sunlight. Keep this medication away from children.

How do I throw away this medication safely? ​

Pack the medication into a bag and bring it back to the pharmacy where you received the medication from. 

Disclaimer

Please take note that the above is not a complete list of all possible side-effects. If you have any concerns about your medication or if you have other side-effects that you think are caused by this medication, please consult your doctor or pharmacist. If you take more than the recommended dose, please seek medical advice immediately. The information provided on this page does not replace information from your healthcare professional. Please consult your healthcare professional for more information.

This article is jointly developed by members of the National Medication Information workgroup. The workgroup consists of cluster partners (NHG Health, National University Health System and SingHealth), community pharmacies (Guardian, Unity and Watsons) and Pharmaceutical Society of Singapore. The content does not reflect drug availability and supply information in pharmacies and healthcare institutions. You are advised to check with the respective institutions for such information.