Vardenafil

Medication Information Leaflet

​What is this medication for?

Vardenafil is used to treat erectile dysfunction, a condition where you are unable to get or keep an erection firm enough to have sexual intercourse. It works by relaxing the blood vessels in your penis, allowing blood to flow into your penis when you get sexually excited. This medicine will only help you to get an erection if you are sexually stimulated. Therefore it is taken on an as-needed basis.

This medication may also be used for other conditions. Check with your healthcare professional if you are unsure why you are given this medication.

How should I take/use this medication?

  • It usually starts to work  within 1 hour and effective up to 4 hours before sexual activity. 
  • For film coated tablet, the medication may be taken with or without food. However, you may find that this medicine takes longer to start working if you take it with a high-fat meal (such as cheeseburger and french fries)
  • For orodispersible tablet, the medication is best taken on an empty stomach. With dry hands, place the tablet on the tongue, where it will rapidly disintegrate, and then swallow. Tablet will dissolve within seconds, do not take with liquid. It should not be removed from the blister pack until administered. 

What should I do if I forget to take/use this medication?

  • Take this medication on an as-needed basis. 
  • Do not take more than once a day.
  • Do not take more than the dose prescribed to you.

What precautions should I take?

Inform your healthcare professional if: 
  • You are allergic to this medication or any of the other ingredients of this medication
  • You are taking medicines called Nitrates (such as sublingual nitroglycerin (also known as Glycerin Trinitrate or GTN), Isosorbide Mononitrate or Isosorbide Dinitrate), as the combination may lead to a dangerous fall in your blood pressure. Nitrates must be withheld at least 24 hours after the last dose of Sildenafil or Vardenafil, and 48 hours after the last dose of Tadalafil. Tell your doctor if you are taking any of these medicines which are often given for relief of angina (chest pain).  If you are not certain, ask your healthcare professional. 
  • You are taking medicines called Alpha-1 Blockers (such as Tamsulosin, Terazosin, Prazosin, Alfuzosin), as the combination may further lower your blood pressure. In order to reduce the chances of these symptoms occurring, you should be on a regular daily dose of your Alpha-blocker before you start drugs for erectile dysfunction.
  • You recently had a stroke or a heart attack, low blood pressure or uncontrolled high blood pressure 
  • You have severe heart, liver or kidney  problem 
  • You have certain rare inherited eye diseases (such as retinitis pigmentosa)
  • You have a stomach ulcer or bleeding problem
  • You have a deformity of your penis 

What are some common side-effects of this medication?

  • Facial flushing where the skin on your face feels hot
  • Headache
  • Dizziness
  • Nausea and indigestion
  • Back pain
  • Nasal congestion and sinusitis

What are some rare but serious side-effects that I need to seek medical advice immediately?

Priapism (an erection that will not go away) - If you have an erection that lasts more than 4 hours, get medical help right away. If it is not treated right away, priapism can permanently damage your penis.
Sudden vision loss in one or both eyes - Sudden vision loss in one or both eyes can be a sign of a serious eye problem called non-arteritic anterior ischemic optic neuropathy (NAION). 
Sudden hearing decrease or hearing loss - Some people may also have ringing in their ears (tinnitus) or dizziness.
 
The symptoms of a drug allergy include one or more of the following: 
  • Swollen face/eyes/lips/tongue
  • Difficulty in breathing
  • Itchy skin rashes over your whole body
If you experience any of these symptoms, you should stop your medication and see your healthcare professional immediately.

What food or medication should I avoid when I take this medication?

Avoid taking grapefruit, or grapefruit juice as they may interact with your medication and increase the risk of side-effects.

Drinking alcohol can temporarily weaken your ability to get an erection and may increase the blood pressure lowering effects of the medication, which can be dangerous. To get the maximum benefit from your medication, it is advisable not to drink excessive amounts of alcohol before taking this medication. 

Inform your healthcare professional if you are taking or intend to take any other medication, supplements, traditional medications or herbal remedies.

How should I store this medication?

Store in a cool and dry place, away from direct sunlight. Keep this medication away from children. 

How should I throw away this medication safely?

Pack this medication into a black trash bag and seal it tightly before throwing into the rubbish chute or bin.


Disclaimers
If you take more than the recommended dose, please seek medical advice immediately. The information provided on this page does not replace information from your healthcare professional. Please consult your healthcare professional for more information.


This article is jointly developed by members of the National Medication Information workgroup. The workgroup consists of cluster partners (National Healthcare Group, National University Health System and SingHealth), community pharmacies (Guardian, Unity and Watsons) and Pharmaceutical Society of Singapore. The content does not reflect drug availability and supply information in pharmacies and healthcare institutions. You are advised to check with the respective institutions for such information.

Last updated on September 2019

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Vardenafil

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