Temozolomide is a drug that is used for the treatment of brain tumours.

​​What is this medication use​​d for

Temozolomide is a drug that is used for the treatment of brain tumours.


Dosage and How to Use​​​

It is a capsule that you take by mouth. It can be taken one hour before food with a glass of water or juice.

Missed a D​​​ose

If you miss a dose of Temozolomide, take it as soon as you can if it is within 12 hours of the missed dose. If it is over 12 hours since your missed dose, skip the missed dose and go back to your usual dosing times. You should never take two doses at the same time.


Side Effects, Precautions, Contraindication​

What are the common side effects of Tem​ozolomide?

Temozolomide is usually well tolerated and serious side effects are rare.

Early Side Effects

  • Nausea and vomiting can sometimes occur
  • There are medications available which prevent or decrease these side effects. If you are given these medications, take them when necessary
  • Fatigue
  • Headache
  • ​Constipation

Delayed Side Effects

  • ​A drop in blood cell counts occur after treatments

Inform your doctor if any of the fol​​lowing occurs:

  • Fever of 38°C
  • Bruising or unusual bleeding
  • Skin rash, itching or redness
  • Difficulty in breathing


Handling and St​orage

Store Temozolomide tablets out of the reach of children, at room temperature, away from heat, light and moisture.


Additional Information

Other name: Temodal®


If you have any questions, please call your pharmacist at the National Cancer Centre. The side effects listed above are those that occur frequently. Other side effects may occur. Please contact your doctor to report.


Disclaimer: The National Cancer Centre Singapore does not endorse or promote the use of any product mentioned in this booklet. The information is presented in a summary to provide an understanding and for knowledge only, and may not contain information about all aspects of care. It does not recommend self-management of health problems or replace consultation with your doctor. You should never disregard medical advice or delay seeking treatment because of something you have read in this booklet.

Copyright © National Cancer Centre Singapore

All rights reserved. No part of this publication may be reproduced, stored in a retrieval system, or transmitted, in any form or by any means, electronic, mechanical, photocopying, recording or otherwise, without prior written permission from the publisher.

Document No. PHM-MED-PEM-137/0916

Version 1
Last reviewed: July 2017
Produced by Department of Pharmacy
National Cancer Centre Singapore
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