Medication Information Leaflet
There are certain restrictions in the supply of Rotigotine. Rotigotine is not available in community/retail pharmacies and is only available in selected healthcare institutions via prescriptions from in-house doctors. Please check with your healthcare provider if they are able to supply it.
Rotigotine can be used alone or in combination with other medications (for e.g. Levodopa preparations) in the treatment of Parkinson’s disease. Parkinson’s disease is a progressive disorder of the nervous system that affects body movement. This medication helps to improve muscle control and allows more normal body movements.
Rotigotine can be also used in the treatment of restless leg syndrome. Restless leg syndrome causes uncomfortable sensation in the legs and an uncontrollable urge to move them even when resting or when the body is not active, such as sitting or lying down.
Rotigotine is available in patches of different strengths (2mg/24h, 4mg/24h, 6mg/24h, 8mg/24h) which releases the medication over 24 hours
Rotigotine patch 2mg/24h is used for the treatment of Parkinson’s disease and restless leg syndrome
Rotigotine patch 4mg/24h, 6mg/24h and 8mg/24h are used for the treatment of Parkinson’s disease
You may have to use more than one patch to reach your dose as prescribed by your doctor
Rotigotine patch should not be cut
The patch can be applied to a clean, dry, hairless area on the shoulder, upper arm, abdomen, thigh or flank
Apply the patch on a different area of skin each day. Do not apply the patch on the same area of skin more than once within 14 days.
Remove the patch from pouch immediately before use and press the patch firmly on skin for 30 seconds after removing the adhesive
Avoid exposing the patch to external heat sources (eg. heating pad, hot baths, prolonged exposure to sunlight)
Do not stop using Rotigotine patch without checking with your healthcare professional. When you stop this medication, you may experience withdrawal symptoms. If you need to stop this medication, follow the instructions on how to do so as advised by doctor. Seek medical advice immediately if you have any of the following withdrawal symptoms when lowering the dose or stopping this medication: fever, confusion, severe muscle stiffness, not caring about things, anxiety, depression, feeling tired, trouble sleeping, sweating, or pain.
If you have forgotten to change the Rotigotine patch at your usual time, change it as soon as you remember
If you have forgotten to apply a new Rotigotine patch after removing the old one, apply a new patch as soon as you remember
If it is close to the time for your next dose, skip the missed dose and use a new Rotigotine patch at the usual time on the following day. Do not use two patches to make up for the missed dose.
Inform your healthcare professional if:
You are allergic to this medication or any of the other ingredients of this medication
You are pregnant, planning to become pregnant, or breastfeeding
You have any liver, lung, heart or mental health conditions
You are taking any other medications, including supplements, traditional medications and herbal remedies.
Skin reaction under the patch like redness and itch
To help avoid skin reactions, apply the patch on a different area of skin each day. Do not apply a patch on the same area of skin more than once within 14 days.
Consult a doctor if the skin reaction last longer than a few days or spread outside the area of skin that was covered by the patch
Low blood pressure resulting in sudden dizziness when getting up from a lying or sitting position
Nausea or vomiting
Involuntary movements of the body
The symptoms of a drug allergy include one or more of the following:
Difficulty in breathing
Itchy skin rashes over your whole body
Some rare but serious side effects includes:
New or worsening behaviour or agitation
Hallucinations (seeing or hearing things that are not there)
Strong urge that are hard to control (such as eating, gambling, spending money)
Swelling in arms and legs due to retention of water
If you experience any of these symptoms, you should stop your medication and see your healthcare professional immediately
You should avoid taking alcohol when on Rotigotine.
The following medication may affect the efficacy of Rotigotine. Discuss with your healthcare professional regarding alternative medication:
Metoclopramide, a medication used for vomiting or digestion
Amisulpride and Sulpiride used in the treatment of mental health condition
Store in a cool and dry place, away from direct sunlight. Keep this medication away from children.
Fold the sticky sides of the Rotigotine patch to each other after removal from skin.
Pack the folded patch into a black trash bag and seal the bag tightly before throwing it into the rubbish chute or bin.
Please take note that the above is not a complete list of all possible side effects. If you have any concerns about your medication or if you have other side effects that you think are caused by this medication, please consult your doctor or pharmacist.
If you take more than the recommended dose, please seek medical advice immediately. The information provided on this page does not replace information from your healthcare professional. Please consult your healthcare professional for more information.
This article is jointly developed by members of the National Medication Information workgroup. The workgroup consists of cluster partners (National Healthcare Group, National University Health System and SingHealth), community pharmacies (Guardian, Unity and Watsons) and Pharmaceutical Society of Singapore. The content does not reflect drug availability and supply information in pharmacies and healthcare institutions. You are advised to check with the respective institutions for such information.
Last updated on Mar 2023
This article was last reviewed on
Wednesday, November 22, 2023
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