Medication Information Leaflet
A combination of paracetamol and orphenadrine is commonly used to treat muscle pain. Orphenadrine is a muscle relaxant and paracetamol is used to relieve pain.
You may take this medication with or without food.
Do not take more than two tablets at any time and make sure to space each dose at least four hours apart.
Do not exceed six tablets in 24 hours.
Do not take other paracetamol-containing products while on this medication to prevent overdose.
Combination tablets containing paracetamol and orphenadrine are generally taken on an as- needed basis. Take them regularly only when directed by the doctor.
If you forget to take a dose, take it as soon as you remember. Then take your next dose at the usual time. Do not take two doses to make up for the missed dose.
Inform your healthcare professional if:
You are allergic to paracetamol or any of the other ingredients of this medication
You have a history of
Glaucoma (abnormally high pressure in the eye)
Urinary condition or not being able to empty your bladder
Myasthenia Gravis (an immune disease that causes muscle weakness)
You are pregnant, planning to become pregnant, or breastfeeding
You are taking any other medications, including supplements, traditional medications and herbal remedies.
The symptoms of a drug allergy include one or more of the following:
Difficulty in breathing
Itchy skin rashes over your whole body
Other rare but serious effects that may occur include:
Retention of urine
Persistently fast heartbeat
If you experience any of these symptoms, you should stop your medication and see your healthcare professional immediately.
Avoid taking alcohol with paracetamol and orphenadrine as it may cause too much drowsiness.
Store in a cool and dry place, away from direct sunlight. Keep this medication away from children.
Pack this medication into a black trash bag and seal it tightly before throwing into the rubbish chute or bin.
If you take more than the recommended dose, please seek medical advice immediately. The information provided on this page does not replace information from your healthcare professional. Please consult your healthcare professional for more information.
This article is jointly developed by members of the National Medication Information workgroup. The workgroup consists of cluster partners (National Healthcare Group, National University Health System and SingHealth), community pharmacies (Guardian, Unity and Watsons) and Pharmaceutical Society of Singapore. The content does not reflect drug availability and supply information in pharmacies and healthcare institutions. You are advised to check with the respective institutions for such information.
Last updated on Sept 2021
This article was last reviewed on
Wednesday, November 22, 2023
In partnership with