Lenvatinib is used to treat thyroid, liver and kidney cancers that have spread to other parts of the body.
How should I take or use this medication?
Take Lenvatinib once a day. Take the exact dose that your doctor tells you to.
You may take it with or without food
Do not break open or crush the capsules. Swallow the capsule whole.
Inform your doctor or pharmacist if you have difficulty swallowing
What should I do if I forget to take or use this medication?
If you forget to take a dose, take it as soon as you remember. However, if it is less than 12 hours to your next dose, skip the missed dose and take your next dose at the usual time. Do not take two doses at the same time.
What precautions should I take when taking or using this medication?
Inform your healthcare professional if:
You are allergic to this medication or any of the other ingredients of this medication
You or your partner becomes pregnant or is planning for pregnancy
You should use effective birth control during and for at least one month after stopping treatment
You are breastfeeding
Do not breastfeed during and for at least one week after stopping treatment
You are taking any other medications, including supplements, traditional medications and herbal remedies
You have any other medical conditions (e.g. heart problems, high blood pressure)
You have any recent or upcoming surgery
What are some common side effects of this medication?
Increased blood pressure
Monitor your blood pressure regularly and record it down. Inform your doctor if you notice an increasing trend.
Feeling tired and lack of energy
Do not drive or operate machinery when you feel tired
Diarrhea
Drink plenty of clear fluids to replace those lost (two litres everyday)
Decreased appetite, nausea or vomiting
Take small, frequent meals throughout the day
Mouth sores or ulcers
Rinse your mouth after every meal using an alcohol-free mouthwash or salt water
Brush your teeth with a soft toothbrush
Voice hoarseness
Stomach discomfort
Weight loss
Joint or muscle ache, headache
You may take paracetamol when necessary to help with this
Palms of the hands or soles of the feet may become numb, sore, red or dry
Moisturize these areas daily
Avoid wearing tight-fitting shoes
What are some rare but serious side-effects that I need to seek medical advice immediately?
Symptoms of a drug allergy including one or more of the following:
Swollen face/eyes/lips/tongue
Difficulty in breathing
Itchy skin rashes over your whole body
Abnormal heartbeat, chest pain or shortness of breath
Very bad swelling of hands, feet or lower legs
Dark urine or light coloured stools
Yellowing of your eyes or skin
Very bad diarrhea, nausea, vomiting or stomach pain
Pain while urinating
Abnormal muscle cramps or numbness
Unusual weakness, tiredness or lightheadedness
Unusual bleeding, bruising, black sticky stools or blood in urine
If you experience any of these symptoms, you should stop your medication and see your healthcare professional immediately.
What food or medication should I avoid when I take or use this medication?
Avoid medicines that are known to interfere with heart rhythms.
How should I store this medication?
Store in a cool and dry place, away from direct sunlight. Keep this medication away from children.
How do I throw away this medication safely?
Pack Lenvatinib into a bag and bring it back to the pharmacy where you received the medication from.
If you take more than the recommended dose, please seek medical advice immediately. The information provided on this page does not replace information from your healthcare professional. Please consult your healthcare professional for more information.
This article is jointly developed by members of the National Medication Information workgroup. The workgroup consists of cluster partners (National Healthcare Group, National University Health System and SingHealth), community pharmacies (Guardian, Unity and Watsons) and Pharmaceutical Society of Singapore. The content does not reflect drug availability and supply information in pharmacies and healthcare institutions. You are advised to check with the respective institutions for such information.
Last updated on August 2020
This article was last reviewed on
Saturday, April 30, 2022