Medication Information Leaflet
This medication is used to lighten areas of darkened skin. It reduces the amount of brown pigments (melanin) produced in your skin.
This medication may come in different combinations with other additives such as topical steroid and topical tretinoin.
If you forgot to apply a dose of this medication, apply it as soon as you remember. Skip the dose if it is almost time for the next dose. Apply your next dose at the usual time. Do not apply two doses to make up for the missed dose.
Inform your healthcare professional if:
Prolonged use of hydroquinone has been associated with the development of exogenous ochronosis (a persistent blue-black pigmentation). Therefore, please use as instructed by your doctor and stop after you have achieved the desired lightening effect.
Certain side effects of this medicine are common and may even disappear during treatment. If any of the following side effects on the sites of application do not go away or are severe, please consult your doctor:
If you experience any of the following side effects on the sites of application, please consult your doctor immediately:
For hydroquinone cream that also contain topical tretinoin and steroid as additives, you may experience some additional side effects. If you experience any of the following side effects, please consult your doctor immediately.
Store in a cool and dry place, away from direct sunlight. Keep this medication away from children.
For Tri-Luma: Store in the refrigerator between 2-8°C. Do not freeze.
Pack this medication into a black trash bag and seal it tightly before throwing into the rubbish chute or bin.
Please take note that the above is not a complete list of all possible side effects. If you have any concerns about your medication or if you have other side effects that you think are caused by this medication, please consult your doctor or pharmacist.
If you take more than the recommended dose, please seek medical advice immediately. The information provided on this page does not replace information from your healthcare professional. Please consult your healthcare professional for more information.
This article is jointly developed by members of the National Medication Information workgroup. The workgroup consists of cluster partners (National Healthcare Group, National University Health System and SingHealth), community pharmacies (Guardian, Unity and Watsons) and Pharmaceutical Society of Singapore. The content does not reflect drug availability and supply information in pharmacies and healthcare institutions. You are advised to check with the respective institutions for such information.
Last updated on Oct 2022
This article was last reviewed on Thursday, June 22, 2023