Medication Information Leaflet
Domperidone is used to provide relief from nausea and vomiting.
It may also be used to provide relief from symptoms of indigestion, such as bloating, excessive fullness, stomach discomfort, excessive burping and heartburn after eating.
Domperidone works by blocking the action of a chemical messenger, dopamine, which helps to stop you from feeling sick (nausea) and prevents vomiting. It also works to increase movement of food through the stomach and intestines more easily, which helps to relieve the symptoms of bloating, fullness and indigestion.
Domperidone may also be used for other medical conditions, please check with your healthcare professional.
This medication is usually used for a short period of time, unless advised otherwise by your doctor.
If you forget to take a dose, take it as soon as you remember. Then take your next dose at the usual time. Do not take two doses to make up for the missed dose.
Inform your healthcare professional if:
Consult your healthcare professional if the symptoms do not go away or become bothersome.
The symptoms of a drug allergy include one or more of the following:
Very rarely (affect less than 1% of patients):
If you experience any of these symptoms, you should stop your medication and see your healthcare professional immediately
Certain antibiotics, antifungals, antivirals, heart medications, medications to treat mental or mood disorders may increase the risk of side effects when taken with domperidone.
Avoid taking grapefruit or grapefruit juice when you are taking this medicine as grapefruit may interact with domperidone and increase the risk of side effects.
Store in a cool and dry place, away from direct sunlight. Keep this medication away from children.
Pack this medication into a black trash bag and seal it tightly before throwing it into the rubbish chute or bin.
Please take note that the above is not a complete list of all possible side effects. If you have any concerns about your medication or if you have other side effects that you think are caused by this medication, please consult your doctor or pharmacist.
If you take more than the recommended dose, please seek medical advice immediately. The information provided on this page does not replace information from your healthcare professional. Please consult your healthcare professional for more information.
This article is jointly developed by members of the National Medication Information workgroup. The workgroup consists of cluster partners (National Healthcare Group, National University Health System and SingHealth), community pharmacies (Guardian, Unity and Watsons) and Pharmaceutical Society of Singapore. The content does not reflect drug availability and supply information in pharmacies and healthcare institutions. You are advised to check with the respective institutions for such information.
Last updated on Oct 2022
This article was last reviewed on Thursday, January 12, 2023