Medication Information Leaflet
Credanil/ Sinemet contains two medications: Levodopa and carbidopa.
This medication is used in the treatment of Parkinson’s disease. Parkinson’s disease is a progressive disorder of the nervous system that affects movement. This medication helps to improve muscle control and allows more normal body movements.
Levodopa is converted into a chemical called “dopamine” in the brain which helps to improve the symptoms of Parkinson’s disease. Carbidopa helps Levodopa to work more effectively by slowing down the speed at which Levodopa is broken down in the body.
If you forget to take a dose, take it as soon as you remember. Then take your next dose at the usual time. Do not take two doses to make up for the missed dose.
Inform your healthcare professional if:
The symptoms of a drug allergy include one or more of the following:
Some rare but serious side effects include:
If you experience any of these symptoms, you should stop your medication and see your healthcare professional immediately.
Do not take Credanil/Sinemet if you have taken a medication for depression called a “non-selective monoamine oxidase inhibitor” (MAOI) in the last 14 days. These medicines include isocarboxazid and phenelzine.
Iron supplements (e.g. ferrous gluconate, ferrous sulphate, iron polymaltose) may decrease the absorption of Credanil/Sinemet. Space Credanil/Sinemet at least 2 hours apart from iron supplements.
The following medication may affect the efficacy of Credanil/Sinemet . Discuss with your healthcare professional regarding alternative medication
Store in a cool and dry place, away from direct sunlight. Keep this medication away from children.
Pack this medication into a black trash bag and seal it tightly before throwing it into the rubbish chute or bin.
Please take note that the above is not a complete list of all possible side effects. If you have any concerns about your medication or if you have other side effects that you think are caused by this medication, please consult your doctor or pharmacist.
If you take more than the recommended dose, please seek medical advice immediately. The information provided on this page does not replace information from your healthcare professional. Please consult your healthcare professional for more information.
This article is jointly developed by members of the National Medication Information workgroup. The workgroup consists of cluster partners (National Healthcare Group, National University Health System and SingHealth), community pharmacies (Guardian, Unity and Watsons) and Pharmaceutical Society of Singapore. The content does not reflect drug availability and supply information in pharmacies and healthcare institutions. You are advised to check with the respective institutions for such information.
Last updated on Mar 2023
This article was last reviewed on
Wednesday, November 22, 2023
In partnership with