Melatonin is used for short-term treatment of insomnia (difficulty sleeping).​


What is this medication used for?

Melatonin is used for short-term treatment of insomnia (difficulty sleeping).

Melatonin may also be used for other conditions – check with your doctor

Related: Overcoming Insomnia

Dosage and How to Use

Follow the directions on your medicine label and take the medicine exactly as directed. Take melatonin with or after food.

Prolonged released tablets are to be swallowed whole with water or other liquids. Do not crush or chew or cut into half.

Melatonin should be taken shortly (1-2hours) before going to bed.

Related: Know Your Medication

Side Effects, Precautions, Contraindication

Before using this medicine:

Tell your doctor if you have or have ever had alcohol or drug abuse; lung, liver or kidney disease; sleep apnea or any autoimmune disease.

For Women: Tell your doctor if you are pregnant, plan to become pregnant, or are breastfeeding.

Possible Side Effects

Like all medicines, this medicine may also cause some possible side effects but not everyone experiences them.

Common Side Effects

What can I do about it?

(Generally, affect up to 10% of patients)

Most of the side effects below improve as your body gets used to the medicine. Speak to your doctor or pharmacist if they persist, worsen or become too bothersome.

Tiredness; drowsiness

Avoid driving, or engaging in activities requiring concentration.


Get up slowly from sitting or lying down position.

Nausea or vomiting; stomach discomfort

Take the medicine with or after food.

Take simple meals and avoid rich or spicy foods.

Feeling clumsy or unsteady; a headache

Take the medicine with or after food.

Speak with the doctor if any of these become bothersome.

For Urgent Attention

Check with your doctor as soon as possible if you experience any of the following:

  • Allergic reaction: skin rash, itching, difficulty in breathing, swollen tongue, lips, eyes, or face.

  • Fever

  • Severe chest pain

  • Irregular heartbeat

  • Memory loss of recent events

  • Abnormal thinking or changes in behaviour

  • Unusual excitement, nervousness, irritability or agitation

  • Blurred vision

  • Fainting

  • Seizures (fits)

If you have any concerns about your medicine or have other side effects that you think are caused by this medicine, please consult your doctor or pharmacist.


  • Avoid drinking alcohol while taking this medicine as it can cause excessive drowsiness.

  • Taking some other medicines with melatonin may affect how they work. Be sure that you tell all doctors, pharmacists, dentists and other healthcare providers who treat you about all medicines and natural remedies you are taking.

Related: Do You Know What's Really in the Pill?

Handling and Storage

Store this medicine at room temperature, away from direct light, heat and moisture (not in the bathroom) and out of reach of children.

Throw away any medication that is expired or no longer needed.

Do not share the medicine with other people.

If you have questions/concerns about this medicine, please ask your doctor or pharmacist.

For Medication Enquiries (During Office Hours)

IMH Clinic B/ Sayang Wellness Pharmacy: 63892077

IMH Clinic C (NAMS) Pharmacy: 63893666

Community Wellness Centre Pharmacy: 64715797

Geylang Behavioural Medicine Pharmacy: 67461724

Child Guidance Clinic (HPB) Pharmacy: 64353807

Child Guidance (Sunrise Wing) Pharmacy: 63892410


Institute of Mental Health

Pharmacy Department
10 Buangkok View
Singapore 539747


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