Letrozole Tablet

Letrozole is a drug that is used to treat breast cancer in menopausal women. It works by reducing the production of a hormone, estrogen that is present in the body.

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What is this medication use​​d for

Letrozole is a drug that is used to treat breast cancer in menopausal women. It works by reducing the production of a hormone, estrogen that is present in the body.​

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Dosage a​nd How to Use​

It is a tablet that you take by mouth. It can be taken with food or on an empty stomach with a glass of water or juice.

Missed a Do​​se

If you miss a dose of Letrozole, take it as soon as you can if it is within 12 hours of the missed dose. If it is over 12 hours since your missed dose, skip the missed dose and go back to your usual dosing time.

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Side Effects, Precautio​ns, Contraindication​

What are the common side effects of Letrozole?​

Letrozole is usually well-tolerated and serious side effects are rare 
 
  • Bone pain, joint pain or muscle ache ​

  • Hot flushes can sometimes occur.

    If this occurs, take your tablet at bedtime

  • Tiredness and lack of energy may occur.

    If tiredness is a problem, do not drive a car or operate machinery if you are feeling tired. Avoid alcohol as it may make you feel more tired and drowsy.

  • Osteoporosis

    Calcium supplementation can reduce or prevent bone thining.

  • Hair thinning may occur

    If this occurs, use a gentle baby shampoo and soft brush

Inform your doctor if any of the following occurs:

  • Severe headache or nausea
  • ​Skin rash
  • Chest pain or palpitations
  • Dizziness
  • Swollen extremities
  • Unusual constipation or diarrhea
  • For women: Unexpected vagina bleeding or discharge

 ​​​​​​

Handling and Stora​ge

Store Letrozole tablets out of the reach of children, at room temperature, away from heat, light and moisture.​

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Additional Information

Other name: Femara®​


If you have any questions, please call your pharmacist at the National Cancer Centre. The side effects listed above are those that occur frequently. Other side effects may occur. Please contact your doctor to report.

 
Disclaimer: The National Cancer Centre Singapore does not endorse or promote the use of any product mentioned in this booklet.  The information is presented in a summary to provide an understanding and for knowledge only, and may not contain information about all aspects of care.  It does not recommend self-management of health problems or replace consultation with your doctor.  You should never disregard medical advice or delay seeking treatment because of something you have read in this booklet.
​©2010

Copyright © National Cancer Centre Singapore

All rights reserved. No part of this publication may be reproduced, stored in a retrieval system, or transmitted, in any form or by any means, electronic, mechanical, photocopying, recording or otherwise, without prior written permission from the publisher.

Document No. PHM-MED-PEM-106/0916​

 

 

Version 1
Last Review: June 2017
Produced by Department of Pharmacy
National Cancer Centre Singapore
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Letrozole Tablet

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