Olanzapine

Olanzapine is used to treat and prevent return of psychosis (such as hearing or seeing things which are actually not present, confused or unreal thoughts, or uncontrolled anger).

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​​​What is this medication used for

Olanzapine is used to treat and prevent return of psychosis (such as hearing or seeing things which are actually not present, confused or unreal thoughts, or uncontrolled anger).

It can also be used to treat mania in bipolar disorder (such as elated mood, irritability or increased activity and energy).

Olanzapine may be used for other conditions, check with your doctor.

 

Dosage and How to Use​

Follow the directions on your medicine label and take the medicine exactly as directed. Do not take more or less of it or take it more often than prescribed by your doctor.

Olanzapine may be taken with food or on an empty stomach.

Continue to take this medicine regularly as prescribed even if you feel well. Do not stop taking it without talking to your doctor, otherwise your condition may worsen very quickly.

Olanzapine must be taken regularly for a few weeks before its full effect is felt.

Missed a Dose​​

Take the missed dose as soon as you remember it. However, if it is more than half way between the doses, skip the missed dose and take your medicine at the usual time.

Do not take two doses at the same time to make up for a missed one.​
 

Side Effects, Precautions, Contraindication​​

Before using this medicine:

Tell your doctor if you have or have ever had Parkinson’s disease; Alzheimer’s disease; heart, liver or kidney disease; stroke; diabetes; seizures (fits); enlarged prostrate (in males); severe constipation; glaucoma, blood disorders; phenylketonuria or drug allergies.

FOR WOMEN: Tell your doctor if you are pregnant, plan to become pregnant, or are breast-feeding.

Possible Side Effects​​​

Like all medications, this medication may also cause some POSSIBLE side effects in some people. Everyone responds differently to medications; so not everyone experiences any or all of them.

COMMON (Generally affect up to 10% of patients)
 
Most of these side effects below will get better or go away completely with continued medication taking as your body gets used to this medication. Contact your doctor or pharmacist should they become too bothersome to you.

~ Drowsiness

~ Dry mouth

~ Increased appetite, weight gain (exercise regularly and avoid excess intake of high fat food)

~ Dizziness (can be reduced by getting up slowly from a sitting or lying down position)

~ Weakness

~ Constipation

 

FOR URGENT ATTENTION
Check with your doctor as soon as possible if you have any of the following:
~ Allergic reactions such as skin rash, itching, swelling of the eyes, face or lips, or difficulty in breathing

~ Restless muscle movements in your eyes, tongue, jaw or neck

~ Increased nervousness & trembling

~ Severe muscle weakness

~ Abnormal thinking or changes in behaviour

~ Confusion

~ Tremor (uncontrolled shaking)

~ Seizures (fits)​

If you have any concerns about your medications or if you have other side effects that you think are caused by this medicine, please consult with your doctor or pharmacist.​
 

Precautions while taking this medicine:

  • Olanzapine may make you drowsy or less alert.   Do not drive or operate machinery if affected.  Avoid alcohol.
  • Smoking may decrease the amount of olanzapine that stays in your body.
  • Olanzapine may sometimes worsen blood glucose control in diabetes. Maintain regular check-ups with your doctor.
  • Olanzapine may interfere with your body’s ability to cool down (make you sweat less), causing your body temperature to increase. Use extra care not to be become overheated during strenuous exercise or hot weather.
  • Olanzapine orodispersible formulation contains aspartame as an excipient, thus let your healthcare provider know if you are phenylketouric.
  • When you take this medicine with some other medicines, it may affect how they work. Be sure that you tell all doctors, pharmacists, dentists and other health care providers who treat you about all medicines and natural remedies you are taking.​

 

Handling and Storage​


Store this medicine at room temperature, away from direct light, heat and moisture (not in the bathroom) and out of reach of children.

Throw away any medication that is expired or no longer needed. 

Do not share the medicine with other people.  

Ask your doctor or pharmacist for more information or if you have any questions.

​​


Institute of Mental Health

Pharmacy Department​​
10 Buangkok View
Singapore 539747

For medication enquiries: (during office hours)

IMH Clinic B/ Sayang Wellness: 63892077

IMH Clinic C (NAMS): 63893666

Community Wellness Clinic, Queenstown: 64715797

Community Wellness Clinic, Geylang: 67461724

Child Guidance Clinic (HPB): 64353807

Child Guidance Clinic (Sunrise Wing): 63892410

Email: enquiry@imh.com.sg
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