Ketoconazole

Ketoconazole is​ used to treat infections caused by fungus. These organisms can infect the skin, scalp, fingernails, toenails, mouth, intestinal tract and vagina.

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What is this medication used for

Ketoconazole is used to treat infections caused by fungus. These organisms can infect the skin, scalp, fingernails, toenails, mouth, intestinal tract and vagina.

This medicine may also be used for conditions as determined by your doctor.

​​​

Dosage and ​​How to Use

This medicine should be taken w​​ith meals to increase absorption in your stomach.

For effective treatment, you should complete the full course of medication prescribed, even though there are signs of improvement. This is because fungal infections usually take some time to clear up. If you stop using this medicine too soon, your symptoms may return.​​

​​Missed ​​​a Dose

Take the missed dose as soon as you remember. If it is almost time for the next dose, skip the missed dose.

Do not double the next dose to make up for the missed dose.

​​

Side Effects, Precautions, Contraindication​

What possible side effects​​ may it cause?

Some side effects of this medicine are not unusual. If any of the following effects persist or are severe, consult your doctor:

  • Nausea, vomiting, stomach upset. Taking this medicine with food usually relieves these effects ​​
  • Diarrhoea 

For patients taking ketoconazole:

  • Heart failure. Inform your doctor if you have a history of heart disease or if you are on heart medication, such as calcium channel blockers, as these medications can weaken the pumping action of the heart when taken concurrently. 
  • There are potential interactions when taken with other medication. The blood concentration of warfarin, digoxin, midazolam and ciclosporin may be increased when taken with ketoconazole; there is a risk of muscle weakness if combined with cholesterol lowering drugs such as simvastatin or atorvastatin. Medications such as phenytoin and rifampicin can decrease the blood level of ketoconazole, making it​ less effective.  
  • ​Avoid alcoholic drinks while you are taking this medicine. Alcohol and this medicine can both affect the liver. Alcoholic beverages may also cause stomach pain, nausea, vomiting, headache, or flushing or redness of the face when taken with ketoconazole. 
​Consult your doctor as soon as possible if you develop a new rash soon after starting the medication or if these additional effects occur, as they may indicate more serious side effects:

  • high fever 
  • dark colored urine 
  • pale colored stool 
  • unusual tiredness or weakness 
  • yellow eyes or skin​

What precaut​​ions should I take?

  • For women: Tell your doctor if you are pregnant, plan to become pregnant, or are breast-feeding. 
  • Inform your doctor of any other medications that you are taking. 
  • Inform your doctor if you are taking over-the-counter medicines, including vitamins, minerals, and herbal products. 
  • Do not allow anyone else to take this medication.

​​

Handling and Sto​​rage

  • Keep this medicine away from heat and direct sunlight in a cool, dry place, out of reach of children. 
  • Do not keep this medicine with other medications in the same container. Keep each medicine separately in labeled containers.


When in doubt, consult your doctor or pharmacist

National Skin Centre
1 Mandalay Road, Singapore 308205
Tel: 63508454​​


Dec 2016​

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Ketoconazole

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